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Description
Growth Related Oncogene (GRO)/Cytokine-induced neutrophil chemo attractant 1 (CINC1) was originally purified from media conditioned by IL1beta stimulated rat kidney epithelioid cells (NRK52E). Amino acid sequence that encodes for rat CINC1 was identified in 1989 by Watanabe's group at Toyama Medical and Pharmaceutical University. CINC1 is a member of the alpha (CXC) subfamily of chemokines. Three additional rat CXC chemokines (CINC2alpha, CINC2beta, CINC3/MIP2) have been identified. The protein sequence of CINC1 is 63-67% identical to that of CINC2alpha, CINC2beta, CINC3/MIP2. In addition, GROalpha, GRObeta and GROgamma share 68%, 71% and 69%, identity respectively with CINC1. It has been suggested that CINCs are the rat counterpart of human GROs. Description: Serum. Synonyms: Polyclonal CINC3 antibody, Anti-CINC3 antibody, Chemokine (C-X-C motif) Ligand 3 antibody, SCYB3 antibody, GRO-gamma antibody, GRO3 antibody, MIP-2b antibody, Growth-regulated Protein Gamma antibody, GROG antibody, MGSA gamma antibody, MIP2B antibody, C-X-C Motif Chemokine 3 antibody.
Immunogen
GRO/CINC3 antibody was raised in rabbit using a synthetic peptide corresponding to the Cterminal part of rat GRO/CINC3 as the immunogenSerum