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Description
Growth Related Oncogene (GRO) /Cytokine-induced neutrophil chemo attractant 1 (CINC1) was originally purified from media conditioned by IL1beta stimulated rat kidney epithelioid cells (NRK52E). Amino acid sequence that encodes for rat CINC1 was identified in 1989 by Watanabe's group at Toyama Medical and Pharmaceutical University. CINC1 is a member of the alpha (CXC) subfamily of chemokines. Three additional rat CXC chemokines (CINC2alpha, CINC2beta, CINC3/MIP2) have been identified. The protein sequence of CINC1 is 63-67% identical to that of CINC2alpha, CINC2beta, CINC3/MIP2. In addition, GROalpha, GRObeta and GROgamma share 68%, 71% and 69%, identity respectively with CINC1. It has been suggested that CINCs are the rat counterpart of human GROs. Description: Serum.
Immunogen
GRO/CINC1 antibody was raised in rabbit using synthetic peptides of the Nterminal part of rat GRO/CINC1 as the immunogenSerum