If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
The tight junction is identified as a belt-like region in which two lipid-apposing membranes lie close together (tight junction strands). Tight junction strands of the adjacent cells form tightly connected pairs. The proteins involved in the formation of tight junctions are divided into two categories: 1) integral membrane proteins, such as occludin, claudin and junctional adhesion molecule, JAM and 2) peripheral membrane proteins (cytoplasmic plaque proteins), MAGUK (membraneassociated guanylate kinase) homologue proteins, such as ZO1, 2, 3, cingulin, symplekin, 19B1, and AF6. In human, the claudin superfamily consists of at least 18 members, which are involved in paracellular transport as structural and functional components of tight junctions. Claudins are directly associated with ZO1, 2 and 3 and indirectly with AF6 and cingulin. It is known that Claudin 2 is distributed at liver or kidney in mouse. Description: Serum. Synonyms: Polyclonal Claudin 2 antibody, Anti-Claudin 2 antibody, SP82 antibody.
Immunogen
Claudin2 antibody was raised in rabbit using a synthetic peptide corresponding to part of the C terminal of Mouse Claudin2 (SSPRSAQQPKAKSEFNS) as the immunogenSerum