TPI1 (Triosephosphate isomerase) belongs to the triosephosphate isomerase family. TPI1 catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency). TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. Recombinant human TPI1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW: 28.8 kDa. Pu
Size
50 μg
Concentration
0.5 mg/ml
Applications
RUO
Other Names
TPI1 human Recombinant , Recombinant human TPI1, TPI1, TPI1 Recombinant, Human TPI1, Human Recombinant TPI1, TPI1, TPI1 Recombinant, Human TPI1, Human TPI1, human TPI1, TPI1 Recombinant protein, TPI1 human protein, Human TPI1 protein, Human TPI1 Recombinant protein, TPI1 protein, TPI1 protein, TPI1 Recombinant protein, triosephosphate isomerase, TPI