Adenine Phosphoribosyltransferase (APRT) (AA 1-180) protein
Description
APRT (adenine phosphoribosyltransferase) is a 180 amino acid protein that localizes to the cytoplasm and belongs to the purine/pyrimidine phosphoribosyltransferase family. Existing as a homodimer, APRT functions to catalyze the formation of inorganic pyrophosphate and AMP from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP), a reaction that is essential for both purine metabolism and AMP biosynthesis. It also produces adenine as a by-product of the polyamine biosynthesis pathway. Recombinant human APRT protein was expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: AMP pyrophosphorylase protein, MGC125856 protein, Adenine phosphoribosyltransferase AMP diphosphorylase protein, DKFZp686D13177 protein, MGC129961 protein, Transphosphoribosidase., AMP protein, MGC125857 protein