Purity ~85% (SDS-PAGE). Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. Source: Recombinant protein corresponding to aa1-461 from human ODC1, fused to His-SUMO-Tag at N-terminal and Myc-Tag at C-terminal, expressed in E. coli. AA