Recombinant Human Melanocyte protein PMEL (PMEL), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 63kDa. partial: 25-467aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
ME20-M; ME20MMelanocyte protein Pmel 17Melanocytes lineage-specific antigen GP100Melanoma-associated ME20 antigen; P1; P100Premelanosome protein; Silver locus protein homolog