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Description
This gene is a classical cadherin from the cadherin superfamily.The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.The protein functions during gastrulation and is required for establishment of left-right asymmetry.At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Immunogen
Purified recombinant fragment of human CDH2 expressed in E. coli.