ELISA: 1:5000, Immunohistochemistry: 1:100-1:300, Western Blot: 1:500-1:2000
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Description
MOV10L1 Polyclonal Antibody. Isoform 1: ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity (PubMed:20534472, PubMed:20547853, PubMed:23166510, PubMed:25762440). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (PubMed:20534472, PubMed:20547853, PubMed:23166510, PubMed:25762440). Involved in the primary piRNA metabolic process (PubMed:20534472, PubMed:20547853, PubMed:23166510, PubMed:25762440). Specifically binds to piRNA precursors and promotes
Immunogen
n/a
Other Names
MOV10L1, Putative helicase Mov10l1, Moloney leukemia virus 10-like protein 1, MOV10-like protein 1