Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5)
Description
Purity > 90% as determined by SDS-PAGE. MW: 53.4kDa. Full Length of Isoform 4: 1-326aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.