An 11β-HSD inhibitor; inhibits 11β-HSD1 activity in isolated liver and decreases blood glucose and insulin concentrations in a mouse model of hyperglycemia and hyperinsulinemia at 100 mg/kg; decreases the expression of MCP-1 and TNF-α in adipose tissue and reduces body weight and improves glucose tolerance and insulin sensitivity in a mouse model of high-fat diet-induced obesity; decreases TNF-α, IL-1β, IL-6, and IL-17 protein levels in serum and reduces severity of collagen-induced arthritis in mice