Recombinant Human Store-operated calcium entry-associated regulatory factor (SARAF), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 31.5kDa. Cytoplasmic Domain: 195-339aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Negative regulator of store-operated Ca2+ entry (SOCE) involved in protecting cells from Ca2+ overfilling. In response to cytosolic Ca2+ elevation after endoplasmic reticulum Ca2+ refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca2+ levels, and thus preventing the overload of the cell with excessive Ca2+ ions.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
HBV X-transactivated gene 3 proteinHBV XAg-transactivated protein 3; Protein FOAP-7Transmembrane protein 66