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Description
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human GDF5.
Immunogen
Human GDF5.
Other Names
GDF5; CDMP1; Growth/differentiation factor 5; Cartilage-derived morphogenetic protein 1; Radotermin; growth differentiation factor 5; LAP4; SYNS2; cartilage-derived morphogenetic protein-1; GDF-5; Bone morphogenetic protein 14; BMP-14; CDMP-1; Lipopolysaccharide-associated protein 4; LAP-4; LPS-associated protein 4; BMP14