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Description
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Synonyms: Monoclonal BMP4 antibody, Anti-BMP4 antibody, BMP-4 antibody, Bone Morphogenetic antibody, 4 antibody, BMP-2B antibody, DVR4 antibody.
Immunogen
BMP4 antibody was raised in mouse using highly pure recombinant human BMP-4 as the immunogen.