A potent, reversible broad spectrum inhibitor of zinc-containing proteases; inhibits thermolysin and elastase, both with Ki values of 20 nM; inhibits MMP-1, -2, -7, -8, -9, -12, -13, -14, -16, and -26 with Ki or IC50 values between 0.1 and 10 nM; inhibits ADAM9, ADAM10, ADAM12, and ADAM17 at nanomolar concentrations