Binding immunoglobulin protein (BiP) belongs to the family of ~70 kDa heat shock proteins (HSP 70). It is a stress response protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding as well as for the maintenance of cell homeostasis and the prevention of apoptosis. Recombinant human BIP protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: Binding immunoglobulin protein protein, Heat Shock 70kDa Protein 5 protein, glucose-regulated protein 78kD protein, Immunoglobulin Heavy Chain Binding Protein., Endoplasmic reticulum lumenal Ca2+ binding protein grp78 protein, GRP78 protein, BIP protein, HSPA 5 protein, Binding immunoglobulin protein 78 kDa glucose regulated protein protein, HSPA5 protein, MIF2 protein, heat shock 70kDa protein 5 protein, GRP78 protein, FLJ26106 protein, GRP 78 protein, Glucose Regulated Protein 78kDa protein