An activator of PKCε; activates PKCε with a >7-fold stronger potency over PKCα, βI, βII, γ, δ, μ, η, and ζ in a cell-free assay; activates PKC in PC12 cells in a concentration-dependent manner; decreases intracellular levels of Aβ in Neuro2 neuroblastoma cells transfected with human APPSwe/PS1Δ9; stimulates hippocampal glutamate release, striatal dopamine release, and hypothalamic serotonin release in rat brain slices in a PKC- and α7-containing nAChR- dependent manner; prevents synaptic loss and amyloid plaque formation and decreases escape latency in the Morris water maze in the 5XFAD transgenic mouse model of Alzheimer's disease at 3 mg/kg