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Description
Rabbit Anti-LCK (Phosphorylated S540) Polyclonal Antibody (PTM-CBPAB-0795YC). Provided herein is a Rabbit polyclonal antibody against LCK Proto-Oncogene, Src Family Tyrosine Kinase. The antibody can be used for immunoassay techniques, such as ELISA, WB. LCK is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
Immunogen
Synthetic peptide corresponding to human Lck around the phosphorylation site of S540