Purity > 90% as determined by SDS-PAGE. MW: 26.8kDa. Extracellular Domain: 22-242aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 2 and 3 may be potent inhibitors of type I IFN receptor activity.