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Description
KANK1 Polyclonal Antibody. Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
Immunogen
n/a
Other Names
KANK1, KN motif and ankyrin repeat domains 1, Kidney ankyrin repeat-containing protein, KANK, Ankyrin repeat domain-containing protein 15, ANKRD15