Recombinant Human Heterogeneous nuclear ribonucleoprotein L (HNRNPL)
Description
Purity > 90% as determined by SDS-PAGE. MW: 80.1kDa. Full Length: 1-589aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elents. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive elent (nCaRE) B2 of the APEX2 promoter.