Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) (C-Term)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human
Isotype
n/a
Format
purified
Size
50 μg
Concentration
n/a
Applications
Western Blotting (WB)
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Description
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. Synonyms: Polyclonal KLRC1 antibody, Anti-KLRC1 antibody, killer cell lectin-like receptor subfamily C, member 1 antibody, CD159A antibody, MGC13374 antibody, MGC59791 antibody, NKG2 antibody, NKG2A antibody.
Immunogen
KLRC1 antibody was raised in rabbit using the C terminal of KLRC1 as the immunogen