Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1)
Clone
18d3
Host Species
Rat
Reactive Species
mouse
Isotype
IgG2a
Format
purified
Size
0.5 mg
Concentration
n/a
Applications
Flow Cytometry (FACS)
Reviews / Ratings
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Description
CD94 is expressed on the surface of NK cells, NK T cells and some memory phenotype CD8 + cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1 b and results in a CD94 high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E, these cells express CD94 on the surface in a form that does not bind Qa-1 b and is believed to be nonfunctional, producing a CD94 low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.
Immunogen
CHO cells transfected with the B6 allele of CD94 1