Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1)
Clone
HP-3D9
Host Species
Mouse
Reactive Species
human
Isotype
IgG1
Format
unconjugated
Size
100 tests
Concentration
n/a
Applications
Flow Cytometry (FACS)
Reviews / Ratings
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Description
CD94, also known as KLRD1 (killer cell lectin-like receptor D1), is a transmembrane glycoprotein of the C-type lectin family, which forms disulfide-linked heterodimers with NKG2A, B, C, E, H proteins, constituting functionally distinct receptors of NK cells and related cell types. CD94/NKG2A and CD94/NKG2B heterodimers serve as inhibitory, whereas CD94/NKG2C and CD94/NKG2E as activating receptors. The ligand for CD94/NKG2 complexes has been identified as HLA-E. Extent of CD94 expression on NK cell surface can be used to demonstrate their progress through the differentiation process.