A cephalosporin antibiotic; active against clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. marcescens, and E. cloacae in vitro (MICs = 0.013-6.25 μg/ml); active against various Gram-positive and Gram-negative bacterial infections in mice (ED50s = 0.016-66 mg/kg); increases survival in a mouse model of K. pneumoniae infection (SD50 = 7.6 mg/kg); curative in a mouse model of P. mirabilis urinary tract infection (CD50s = 0.4-0.75 mg/kg)