Source: Active recombinant N-terminal His-tagged enzyme amino acids 1-355 expressed in E. coli ? Mr: 43.7 kDa ? SIRT6 associates specifically with telomeres and functions at chromatin to decrease NF-κB signaling. Mammalian cells depleted of SIRT6 display abnormal telomere structures similar to defects found in Werner syndrome, a premature aging disorder associated with a shortened life span.
Size
100 μg
Concentration
n/a
Applications
n/a
Other Names
NAD-dependent Deacetylase 6|Silent Information Regulator 6|SIR2-like Protein 6|SIR2L6|Sirtuin 6