Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) (AA 278-286) peptide
Description
This peptide is amino acids 278 to 286 fragment of MAGE protein. It was found to be presented by HLA-A 0201 molecules on the surface of a human breast carcinoma cell line. MAGE-A1 tumor antigen can fully activate the mouse peptide-specific CTL lines to produce IFN-gamma. Tumor-specific shared antigens, such as those of the MAGE gene family, are expressed by tumors of different histological types.