8,11,14-Eicosatriynoic acid is an inhibitor of prostaglandin and leukotriene biosynthesis as well as arachidonic acid induced platelet aggregation.{14705} It inhibits cyclooxygenase (IC50 = 14 μM), human 12-lipoxygenase (IC50 = 0.46 μM), 5-lipoxygenase (IC50 = 25 μM) and the actions of slow-reacting substance of anaphylaxis (SRS-A) (IC50 = 10 μM).{14704,14706}