1-588aa, Full length protein. MW: 59,838 Da. Purity >85% (SDS-PAGE). The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and This protein is thought to be a signal transducer that interacts with protein kinase pathways to