Recombinant Mouse DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) , partial
Description
MW: 77,824 Da. Purity >85% (SDS-PAGE). CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Al
[DNA (cytosine-5)-methyltransferase 3A isoform 1; DNA (cytosine-5)-methyltransferase 3A; DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase 3A; DNA methyltransferase MmuIIIA; DNA MTase MmuIIIA; M.MmuIIIA]