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Description
RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. Synonyms: Polyclonal RAD17 antibody, Anti-RAD17 antibody, RAD17 homolog, S. pombe antibody, CCYC antibody, HRAD17 antibody, R24L antibody, RAD17Sp antibody, Rad24 antibody.
Immunogen
RAD17 antibody was raised in rabbit using the C terminal of RAD17 as the immunogen