Cell Cytotoxicity Assay Kit II (WST-SRB-Crystal Violet)
Description
Cytotoxicity assays are essential tools in drug discovery. In vitro single parameter cytotoxicity assays, such as using tetrazolium salt (WST), sulforhodamine B (SRB) or crystal violet (CV) are widely used in cultured cellsin order to assess the cytotoxicity of potential drug candidates as these methods are fast, reproducible, and do no require using living mammals during early drug discovery stages. However, the most critical problem of using single parameter assays is the determination of their IC50 data offers a limited perspective and can lead to erroneous assumptions or erroneous, unsucessful results when the selected candidates are used in more complex models (false positives). On the other hand, if the cytotoxicity assay is not selec
Size
1000 assays
Concentration
n/a
Applications
The assay measures cell cytotoxicity in response to synthetic compounds and can be adapted for HTS applications