2-226aa; Partial. MW: 28.9kD. Purity >90% as determined by SDS-PAGE. Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.
Size
0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg
Concentration
n/a
Applications
n/a
Other Names
[Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog]
A mammalian telomerase-associated protein.Harrington L., McPhail T., Mar V., Zhou W., Oulton R., Bass M.B., Arruda I., Robinson M.O.Science 275:973-977(1997) The full-ORF clone resource of the German cDNA consortium.Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.BMC Genomics 8:399-399(2007) Human telomerase cont