MW: 105,393 Da. Purity >85% (SDS-PAGE). This protein is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.
Size
n/a
Concentration
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Applications
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Other Names
[eukaryotic translation initiation factor 4E transporter isoform a; Eukaryotic translation initiation factor 4E transporter; eukaryotic translation initiation factor 4E transporter; eukaryotic translation initiation factor 4E nuclear import factor 1; Eukaryotic translation initiation factor 4E nuclear import factor 1]