Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identifiedin rodents. Murine C10 is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4.It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and alsoexhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 containsthe four highly conserved cysteine residues present in CC chemokines. MW: 10.7 kDa. Purity > 97% by SDS-PAGE and HPLC analyses
Size
2 ug, 10 ug, 1 mg, 100 ug, 250 ug, 500 ug
Concentration
Lyophilized from a 0.2 μm filtered concentrated solution in 20mM Tris, pH 8.0, 500mM NaCl.