Purity ~99% (HPLC). A very potent and highly selective peripheral resctricted u-opioid receptor agonist (Ki = 2nM). Often used as an antidiarrheal, antipruritic, and antihyperalgesic agent. In addition, shown to improve defective post-receptor insulin signaling in skeletal muscle cells and enhance insulin sensitivity in rats. Solubility: DMSO or Warm EtOH Primary Target: u opioid receptor Primary Target Ki: 2nM