Recombinant Human Proheparin-binding EGF-like growth factor (HBEGF), partial
Description
Purity > 85% as determined by SDS-PAGE. MW: 11.7kDa. Partial: 63-148aa. C-terminal 6xHis-tagged. Homo sapiens (Human). Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Diphtheria toxin receptor; Short name:DT-R; DTR, DTS, HEGFL