Purity > 90% as determined by SDS-PAGE. MW: 60.2kDa. Full Length: 1-299aa. N-terminal GST-tagged. Homo sapiens (Human). Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
B-cell receptor-associated protein BAP37; D-prohibitin; Repressor of estrogen receptor activity