Endothelial Differentiation Related Factor 1 (EDF1) (AA 1-148) protein (His tag)
Description
EDF1 controls endothelial cell differentiation. EDF1 has a role as a bridging protein that interconnects regulatory proteins and the basal transcriptional machinery, thus modulating the transcription of genes that take part in endothelial differentiation. EDF1 binds calmodulin through its IQ domain and controls nitric oxide synthase activity via calmodulin sequestration in the cytoplasm. EDF1 is localized in adult liver, heart, adipose tissues, intestine and pancreas Synonyms: EDF-1, MBF1, Multiprotein-bridging factor 1