??Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.Adeno-associated viruses (AAVs) are derived from defective parvoviruses, which depend on essential helper functions provided by other viruses, such as adenovirus and herpes virus, for efficient viral replication and propagation. AAV has no etiologic association with any known diseases and has been successfully used to establish efficient and long-term gene expression
1. Auricchio, A., Hildinger, M., O'Connor, E., Gao, G. P. and Wilson, J. M. (2001) Hum Gene Ther 12:71-6. 2.Brument, N., Morenweiser, R., Blouin, V., Toublanc, E., Raimbaud, I. et al. (2002) Mol Ther 6:678-86. 3.Clark, K., Liu, X., McGrath, J., and Johnson, P. (1999) Hum. Gene Ther., 10, 1031-1039. 4.Graham, F. L., Smiley, J., Russell, W. C. and Nairn, R. (1977) J Gen Virol 36:59-74. 5.Grimm, D. and Kleinschmidt, J. A. (1999) Hum Gene Ther 10:2445-50. 6.Matsushita, T., Elliger, S., Elliger, C.,