BCL2L11, 1-138aa, Human, His tag, E.coli (Denatured)
Description
Purity: > 80% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer, pH8.0, 2M urea, 20% glycerol 5mM DTT, 300mM NaCl . BCL2L11 (Bcl-2-like protein 11) belongs to the Bcl-2 family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The expression of BCL2L11 can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney. Recombinant human BCL2L11 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Size
250ug, 50ug, 10ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
BCL2-like 11, BAM, BIM, BIM-alpha6, BIM-beta6, BIM-beta7, BimEL, BimL, BOD