RXR-alpha (Retinoid x receptor),111-228aa, Human, E.coli
Description
Purity: > 95% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM beta-Mercaptoethanol . The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms ; RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms(RXR alpha1, RXR alpha2). The DNA binding domain of RXR(111-228aa) was over expressed in E.coli and purified by using conventional column chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Retinoid X receptor alpha, RXRA, NR2B1, RXR-alpha, Retinoid x receptor, Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1, Retinoic acid receptor RXR-alpha, FLJ16020, FLJ16733, MGC102720, Retinoic acid receptor RXR alpha, RXR alpha1, RXRalpha1, RXRA1