MW: 14.4 kDa (140aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson. Recombinant mouse alpha-Synuclein, was expressed in E Coli and purified by using conventional chromatography techniques
Size
0.1 mg, 0.5 mg
Concentration
1mg/ml (determined by BCA assay)
Applications
SDS-PAGE
Other Names
[alpha-Synuclein; Snca; Syn; alpha-Synuclein; NACP; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor]
ueda K., et al. (1993) Proc. Natl. Acad. Sci. uSA 90:11282-11286 ; Kim J., et al. (1997) Molecules and Cells 7:78-83 ; Jakes R., et al. (1994) FEBS lett. 345:27-32. ;