MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and pancreas. MW: 35.2 kDa (335 aa, 25-338 aa + NT His Tag). Purity ≥95%
Size
50 μg
Concentration
1 mg/ml
Applications
RUO
Other Names
Malate dehydrogenase 2, NAD (mitochondrial), M-MDH, MDH, MOR1