Recombinant Human V-set domain-containing T-cell activation inhibitor 1 (B7H4), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 52.6kDa. Partial: 26-258aa. N-terminal GST-tagged. Homo sapiens (Human). Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.