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Description
The inhibitory glycine receptor (GlyR) is a member of the ligand-gated ion channel superfamily of neurotransmitter receptors. It shows a widespread expression profile in brain. Several isoforms and splice variants with distinct pharmacology have been discovered so far.
Immunogen
Purified rat spinal chord glycine receptor. Epitope: aa 96 - 105 of mature glycine receptor α1-subunit.
Defective Escape Behavior in DEAH-Box RNA Helicase Mutants Improved by Restoring Glycine Receptor Expression.Hirata H, Ogino K, Yamada K, Leacock S & Harvey RJ. Journal of Neuroscience 33: 14638-44, 2013. / Distribution of the glycine receptor β-subunit in the mouse CNS as revealed by a novel monoclonal antibody. Weltzien F, Puller C, O'Sullivan GA, Paarmann I & Betz H. Journal of Comparative Neurology 520: 3962-81, 2012. / Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina. Hoon M, Soykan T, Falkenburger B, Hammer M, Patrizi A, Schmidt KF, Sassoe-Pognetto M, Lowel S, Moser T, Taschenberger H, Brose N & Varoqueaux F. Proceedings of the National Academy of Sciences USA 108: 3053-8, 2011.