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Description
CD272 Polyclonal Antibody, Alexa Fluor? 750 Conjugated. ? Target Background: B and T lymphocyte attenuator (BTLA), an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, and attenuates produ
Immunogen
KLH conjugated synthetic peptide derived from human B and T-lymphocyte attenuator. Immunogen Range: 239-289/289
Other Names
BTLA1; CD272; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA