Recombinant Human Toll-like receptor 7 (TLR7), partial
Description
Purity > 85% as determined by SDS-PAGE. MW: 29.5kDa. Partial: 861-1049aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.