Recombinant Human Transcription elongation factor A protein 2 (TCEA2)
Description
Purity > 90% as determined by SDS-PAGE. MW: 49.6kDa. Full Length: 1-299aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Necessary for efficient RNA polymerase II transcription elongation past tplate-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Testis-specific S-IITranscription elongation factor S-II protein 2Transcription elongation factor TFIIS.l