Recombinant Human Transcription factor PU.1 (SPI1)
Description
Purity > 85% as determined by SDS-PAGE. MW: 35.1kDa. Full Length: 1-270aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing